Last updated: May 2026
Botox, Dysport, and Xeomin are all FDA-approved neuromodulators that reduce wrinkles by relaxing muscles. Botox is the most widely used ($10–$15/unit), Dysport spreads more and may work faster ($4–$6/unit but requires more units), and Xeomin is a "naked" neurotoxin with no additives ($10–$15/unit). Results last 3–4 months for all three.
| Feature | Botox | Dysport |
|---|---|---|
| Cost | $10 - $15 per unit | $4 - $6 per unit (2.5-3x units needed) |
| Recovery | None | None |
| Longevity | 3-4 months | 3-4 months |
Botox stays more localized; Dysport diffuses more widely — this makes Dysport better for broad areas like the forehead and Botox better for precise spots like crow's feet
Dysport may kick in 1–2 days faster than Botox
Xeomin has no complexing proteins, which may reduce the risk of developing antibody resistance over time
Per-treatment cost is roughly similar across all three ($300–$600 per area) despite different per-unit pricing
All three last about 3–4 months, though individual results vary
For most patients, the differences between Botox, Dysport, and Xeomin are subtle. Botox is the safe, well-known choice with the most experienced injectors. Dysport is worth trying if you want faster results or are treating broad forehead lines. Xeomin is a smart option if you've noticed Botox becoming less effective over time (possible antibody resistance). Many experienced injectors use all three and will recommend based on your specific anatomy and treatment goals.
Dysport costs less per unit ($4–$6 vs. $10–$15 for Botox), but you need roughly 2.5–3 times more units of Dysport to achieve the same effect. When calculated per treatment area, the total cost is typically similar — ranging from $300 to $600 per area for both products.
Xeomin (incobotulinumtoxinA) is sometimes called "naked Botox" because it contains only the active neurotoxin without the complexing proteins found in Botox and Dysport. This may reduce the chance of your body developing antibodies that make the treatment less effective over time. Results and duration are comparable to Botox.
Yes, you can switch between neuromodulators. Many patients try different products to see which works best for them. Some injectors even use different products on different areas of the same face in one session. There's no medical reason you can't switch.
Clinical studies show all three products last approximately 3–4 months for most patients. Some patients report Dysport wearing off slightly sooner, while others find no difference. Individual variation in muscle strength, metabolism, and activity level affects duration more than the product itself.